Luis began his PhD candidature in infectious disease epidemiology at the National Centre for Epidemiology and Population Heath in 2014. He is a medical graduate from the Universidad Peruana Cayetano Heredia (Peru) and last year he completed the MEpi and MPH at the University of Queensland.
Clostridium difficile is the most common cause of antibiotic associated diarrhea among hospital inpatients. The incidence and severity of C. difficile infection have increased worldwide in the last two decades and it is largely due to the emergence of hypervirulent C. difficile strains. Of great concern is the identification of hypervirulent C. difficile PCR ribotype 027 infection cases in Australia. It is imperative to understand the epidemiology of C. difficile and assess the risk of outbreaks of severe C. difficile cases in Australia; therefore, the proposed PhD project aims (1) to determine the C. difficile ribotypes associated with hospital and community-acquired C. difficile disease in Brisbane and Perth, and changes in the ribotype profile over three years and (2) to determine the prevalence of C. difficile colonization in asymptomatic patients of two major Australian tertiary hospitals in Brisbane and Perth and changes in prevalence over three years.