The Centre of Research Excellence (CRE) in Medicines and Ageing is a multi-disciplinary collaboration between enthusiastic, highly dedicated and internationally recognised researchers from the University of Sydney, Australian National University, the Sax Institute, University of Western Australia, University of NSW, University of Technology Sydney, and the Institute for Clinical and Evaluative Sciences in Canada. Professor Emily Banks heads the ANU node of CREMA as a Chief Investigator, and leads several researchers who contribute to projects as part of CREMA. Using large linked databases of routinely collected medicines and other health information, CREMA produces much-needed, quantitative evidence on the real-world use, harms, costs and cost-effectiveness of specific medicines. CREMA investigators also work closely with agencies to influence national pharmaceutical policy decisions and health professionals making important treatment decisions with their patients.